A MULTIPLE RIBOSOMAL STRUCTURE IN PROTEIN SYNTHESIS
نویسندگان
چکیده
منابع مشابه
Protein synthesis in rabbit reticulocytes: Characteristics of a ribosomal factor that reverses inhibition of protein synthesis
A ribosomal salt (0.5 M KCI) wash factor (RF) that reverses inhibition of protein synthesis in heme-deficient reticulocyte lysates has been resolved from the bulk of MettRNAfmet-binding factor (EIF-1), Co-EIF-I, and EIF-2 (ternary complex dissociation factor, TDF). The purified RF restores protein synthesis activity of heme-deficient lysates to the level observed in the presence of hemin. No di...
متن کاملTetracycline inhibition of Mycoplasma ribosomal protein synthesis.
Polyuridylic acid directed protein synthesis by ribosomes from tetracyclinesensitive and tetracycline-resistant cells of Mycoplasma laidlawii B was found to be sensitive to tetracycline. The ribosomal preparations were somewhat more sensitive to tetracycline than mixtures of ribosomes and cell membrane fragments. No requirement for an exogenous m-RNAcould be demonstrated with the latter prepara...
متن کاملStructure of a ribosomal protein gene in Mucor racemosus.
As an extension of our analysis of the translational apparatus of Mucor racemosus we have isolated a gene encoding a ribosomal protein of Mucor. Based on a method developed for S. cerevisiae, we identified by hybrid selection and in vitro translation a lambda-Charon 4A clone containing the genomic copy of a Mucor ribosomal protein. The gene consisted of two exons of 57 and 387 nucleotides. The ...
متن کاملRole of ribosomal subunits in protein synthesis in mammalian cells.
Exchange of ribosomal subunits (RSU) in the course of protein synthesis has been demonstrated in bacteria." 2 RSU have been shown to be stable during bacterial growth and to be continuously recycled through ribosomes.2 These results suggested that ribosomes dissociate into subunits between successive rounds of protein synthesis. The 30S E. coli RSU binds the initiator tRNA (formylmethionine-tRN...
متن کاملRegulation of ribosomal protein synthesis in Escherichia coli.
The kinetics of synthesis of ribosomal, nonribosomal, and total protein, and of ribosomal ribonucleic acid (RNA), were measured in Escherichia coli during a shift-up involving a doubling of specific growth rate. The increase in ribosomal protein synthesis was not accompanied by a corresponding decrease in non-ribosomal protein synthesis. Thus, the average rate of protein synthesis per ribosome ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1963
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.49.1.122